Research-First Biotech

Programmable Neurobiology for Cognitive Health

Operating in stealth, with selective partnering and confidentiality.

Guided by careful science and responsibility in brain-related research.

Pioneering the Future of Cognitive Health

Manhattan Neuroscience is a research-driven biotechnology company exploring new approaches to brain health, bringing together a world-class team and selective partnerships to unlock new frontiers in neuroscience, computation, and biological understanding.

Our Approach

Computational Discovery

AI-guided hypothesis generation for multi-target biology.

Experimental Validation

Human-relevant models, multi-omics readouts, and rigorous replication.

Translation Path

Partnership, regulatory-minded development, and clear milestones.

Our Primary Research Domains

We apply our research framework across a small number of preclinical focus areas where regulatory biology and computation intersect.

Gene Regulation & Programmable Neurobiology

Neurodegeneration & Cognitive Aging (Preclinical)

Precision Neuropsychiatry (Preclinical)

AI-Driven Drug Discovery & Experimental Loops

Meet Our Advisors

  • An older man with white hair and a white beard, wearing glasses, a blue button-up shirt, and a brown jacket, standing with arms crossed against a plain background.

    George Church, PhD

    Professor of Genetics at Harvard Medical School, and Founding Core Faculty Member of the Wyss Institute for Biologically Inspired Engineering.

  • A man with brown hair, a beard, wearing red glasses, a black pinstripe suit, white shirt, and a purple tie, smiling at the camera.

    Glenn Cohen, JD

    Deputy Dean at Harvard Law School, James A. Attwood and Leslie Williams Professor of Law, and Faculty Director of the Petrie-Flom Center for Health Law Policy, Biotechnology, and Bioethics.

  • Headshot of a middle-aged man in a dark suit and white shirt, smiling gently and facing the camera.

    Jerrold Rosenbaum, MD

    Stanley Cobb Professor of Psychiatry at Harvard Medical School, and Emeritus Chair of Psychiatry at Massachusetts General Hospital.

  • A smiling middle-aged man with gray hair wearing a gray plaid suit, white shirt, and patterned tie.

    Maurizio Fava, MD

    Psychiatrist-in-Chief at Massachusetts General Hospital; Chair of Psychiatry for Mass General Brigham Academic Medical Centers.

  • A middle-aged man with dark hair, light skin, and a goatee, wearing a checkered shirt and a dark blazer, smiling at the camera.

    Stephen Haggarty, PhD

    Director of the MGH Chemical Neurobiology Laboratory, Professor of Neurology at Harvard Medical School, and Senior Associate at the Broad Institute of Harvard/MIT.

  • A professional headshot of a man with short brown hair, wearing a black suit jacket and white dress shirt, smiling against a plain background.

    Jacob Hooker, PhD

    Lurie Family Professor of Radiology at Harvard Medical School and Director of Radiochemistry at Massachusetts General Hospital.

  • Portrait of a man in a dark blue suit and white shirt, smiling at the camera with a plain dark background.

    Brendan Hussey, PhD

    President and CEO of Zymgeist Labs, Vice President at JLS Fund, former Associate at Stifel Investment Banking, with a background in Synthetic Biology from the University of Toronto.

  • A professional woman with straight auburn hair wearing a black blazer over a maroon striped shirt, gold necklace, and earrings, posing against a dark background.

    Dominique Russo, MBA, MPA

    Founder of Stealth in Silicon Valley and the Gulf Cooperation Council, Vice-Chair of the IEEE Group on Extended Reality (XR), and advisor guiding national leaders in innovation and AI-powered national strategy.

  • A young man with short brown hair and a beard, wearing a white shirt and a dark blazer, smiling at the camera against a black background.

    John Granata, MEng

    Product Director at Coinbase, former Director of Engineering at Coinbase, with a background in Electrical Engineering and Computer Science from the Massachusetts Institute of Technology.

  • A young man with wavy brown hair, blue eyes, and a beard, wearing a light blue and white striped button-up shirt, smiling against a black background.

    Logan Fahrenkopf, JD

    Associate at Wilson Sonsini Goodrich & Rosati, with experience at Regeneron Pharmaceuticals and involvement in multiple Harvard Law initiatives, including the Intellectual Property Law Association, the Entrepreneur Project, and the Journal of Law and Technology.

  • Portrait of a young woman with long red hair, blue eyes, wearing a black pinstripe blazer and white blouse, against a black background.

    Lily O’Brien, LLM

    Law studies at the University of Oxford, Academic Scholar at Christ Church, graduate of The University of Law, with additional studies at Panthéon-Assas University and a Certificate Supérieur de Droit Français et International.

  • A young woman with long blonde hair, blue eyes, and fair skin, wearing a black blazer and a blue and white striped collared shirt, looking at the camera with a slight smile.

    Amie Leighton, BA

    Co-Founder of Allia Health, focused on Precision Psychiatry, with studies at the University of Oxford and Christ Church.

  • A portrait of a man with short, curly dark hair, wearing a black collared shirt, against a black background.

    Ben Cyrulnik, MS

    Investment Associate at JLS Fund, Patent Analyst at Calyx Law, with a background in Pharmaceutical Science from the University of Wisconsin–Madison.

  • A young man with dark hair, wearing glasses, a white shirt, a patterned tie, and a black suit jacket, smiling against a black background.

    Nick Castoria, MBA 2026

    Harvard Business School, Strategy Consultant at Accenture, University of Pennsylvania Class of 2019, and participant in Sponsors for Educational Opportunity (SEO).

Our

Talent

Invitation

We’re assembling a small, exceptional team at the intersection of AI, genomics, and experimental biology. If you want to build rigorous, human-relevant neuroscience biotech—while protecting IP and moving fast with scientific discipline—we’d love to hear from you.

Who We’re Looking For

AI Drug Discovery

Foundation models for biology/chemistry, active learning, evals, and scientific software.

Gene Regulation / TF Biology

Gene regulatory networks, perturbation biology, and CRISPR screens—wet or dry.

Genomics and Multi-omics

Single-cell, epigenomics, causal inference, and integrative analysis.

Translational Experimentalists

Human cell models, assay development, and reproducibility-first workflows.

Operator-Builders

Platform engineering, data infrastructure, and lab automation interfaces.

Start a Conversation

Manhattan Neuroscience is assembling a world-class team and establishing strategic partnerships to advance the frontiers of neuroscience. Whether you are an investor, funder, or potential research collaborator, we invite you to connect with us via the form below. We will review all messages carefully and respond selectively.